MSc BIOCHEMISTRY
DRUG DISCOVERY & STRUCTURAL BIOLOGY

FEDERICO TOGNALI

MSc Biochemistry candidate at Sapienza - University of Rome, leveraging integrated structural biology to revolutionize drug discovery. Graduated Summa Cum Laude while working full-time for four years — forging the precision and grit I now bring to the lab. I am profoundly hungry to translate these multi-scale structural insights into the design of next-generation therapeutics.

Master's Thesis

Sapienza University of Rome | Forthcoming 2026

Proposed research focus on integrated structural methods for drug discovery. The project aims to explore the synergy between diverse structural biology techniques to characterize therapeutic targets and optimize small-molecule interactions, bridging the gap between molecular architecture and pharmaceutical development.

Crystallographic Quality and Beyond

National Research Council (CNR), ITACA.SB Workshop | February 2026

  • Selected for an intensive program focused on the latest advancements in structure-based drug discovery.

  • Deepened understanding of protein crystallization and X-ray diffraction through direct exposure to world-leading pioneers.

  • Gained strategic insights into complex structural challenges from icons like Martin Caffrey, Terese M. Bergfors and experts from Diamond Light Source and Instruct-ERIC.

Decoding Spatial Transcriptomics

EMBL-EBI Training | April 2026

  • Gained a comprehensive overview of the integration of sequencing and imaging data to resolve complex tissue architecture.

  • Followed advanced modules on bioinformatics workflows and the management of multi-scale structural data.

  • Deepened understanding of the spatial organization of gene expression through direct exposure to state-of-the-art methodologies.

Biochemical Research Internship

University of Milano-Bicocca | Feb 2025 – Apr 2025

  • Investigated the cytotoxic effects of Cadmium and G. officinalis on human adenocarcinoma cell lines.

  • Executed advanced biochemical protocols, including SDS-PAGE, Western Blotting, and MTT assays for protein and metabolic characterization.

  • Performed precise protein quantification using Bradford and BCA assays, ensuring high-standard experimental data.